A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV

RNA polymerase II (RNAPII) is emerging as an important factor in DNA damage responses, but how it responds to genotoxic stress is not fully understood. We have developed a rapid and sensitive flow cytometry method to study chromatin binding of RNAPII in individual human cells through the cell cycle....

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Detalles Bibliográficos
Autores principales: Bay, Lilli T E, Syljuåsen, Randi G, Landsverk, Helga B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410883/
https://www.ncbi.nlm.nih.gov/pubmed/35641102
http://dx.doi.org/10.1093/nar/gkac434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410883/
https://www.ncbi.nlm.nih.gov/pubmed/35641102
http://dx.doi.org/10.1093/nar/gkac434

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