Single base-pair resolution analysis of DNA binding motif with MoMotif reveals an oncogenic function of CTCF zinc-finger 1 mutation

Defining the impact of missense mutations on the recognition of DNA motifs is highly dependent on bioinformatic tools that define DNA binding elements. However, classical motif analysis tools remain limited in their capacity to identify subtle changes in complex binding motifs between distinct condi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lebeau, Benjamin, Zhao, Kaiqiong, Jangal, Maika, Zhao, Tiejun, Guerra, Maria, Greenwood, Celia M T, Witcher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410893/
https://www.ncbi.nlm.nih.gov/pubmed/35947648
http://dx.doi.org/10.1093/nar/gkac658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410893/
https://www.ncbi.nlm.nih.gov/pubmed/35947648
http://dx.doi.org/10.1093/nar/gkac658

Ejemplares similares