The L1-ORF1p coiled coil enables formation of a tightly compacted nucleic acid-bound complex that is associated with retrotransposition

Long interspersed nuclear element 1 (L1) parasitized most vertebrates and constitutes ∼20% of the human genome. It encodes ORF1p and ORF2p which form an L1-ribonucleoprotein (RNP) with their encoding transcript that is copied into genomic DNA (retrotransposition). ORF1p binds single-stranded nucleic...

Descripción completa

Detalles Bibliográficos
Autores principales: Cashen, Ben A, Naufer, M Nabuan, Morse, Michael, Jones, Charles E, Williams, Mark C, Furano, Anthony V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410894/
https://www.ncbi.nlm.nih.gov/pubmed/35871298
http://dx.doi.org/10.1093/nar/gkac628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410894/
https://www.ncbi.nlm.nih.gov/pubmed/35871298
http://dx.doi.org/10.1093/nar/gkac628

Ejemplares similares