MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus

Recent in vitro reconstitution analyses have proven that the physical interaction between the exosome core and MTR4 helicase, which promotes the exosome activity, is maintained by either MPP6 or RRP6. However, knowledge regarding the function of MPP6 with respect to in vivo exosome activity remains...

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Detalles Bibliográficos
Autores principales: Fujiwara, Naoko, Shigemoto, Maki, Hirayama, Mizuki, Fujita, Ken-ichi, Seno, Shigeto, Matsuda, Hideo, Nagahama, Masami, Masuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410898/
https://www.ncbi.nlm.nih.gov/pubmed/35902094
http://dx.doi.org/10.1093/nar/gkac559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410898/
https://www.ncbi.nlm.nih.gov/pubmed/35902094
http://dx.doi.org/10.1093/nar/gkac559

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