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Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations

Genome wide association studies provide statistical measures of gene–trait associations that reveal how genetic variation influences phenotypes. This study develops an unsupervised dimensionality reduction method called UnTANGLeD (Unsupervised Trait Analysis of Networks from Gene Level Data) which o...

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Detalles Bibliográficos
Autores principales: Mizikovsky, Dalia, Naval Sanchez, Marina, Nefzger, Christian M, Cuellar Partida, Gabriel, Palpant, Nathan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410900/
https://www.ncbi.nlm.nih.gov/pubmed/35716123
http://dx.doi.org/10.1093/nar/gkac413