Resistance of mitochondrial DNA to cadmium and Aflatoxin B(1) damage-induced germline mutation accumulation in C. elegans

Mitochondrial DNA (mtDNA) is prone to mutation in aging and over evolutionary time, yet the processes that regulate the accumulation of de novo mtDNA mutations and modulate mtDNA heteroplasmy are not fully elucidated. Mitochondria lack certain DNA repair processes, which could contribute to polymera...

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Detalles Bibliográficos
Autores principales: Leuthner, Tess C, Benzing, Laura, Kohrn, Brendan F, Bergemann, Christina M, Hipp, Michael J, Hershberger, Kathleen A, Mello, Danielle F, Sokolskyi, Tymofii, Stevenson, Kevin, Merutka, Ilaria R, Seay, Sarah A, Gregory, Simon G, Kennedy, Scott R, Meyer, Joel N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410910/
https://www.ncbi.nlm.nih.gov/pubmed/35947695
http://dx.doi.org/10.1093/nar/gkac666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410910/
https://www.ncbi.nlm.nih.gov/pubmed/35947695
http://dx.doi.org/10.1093/nar/gkac666

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