CRISPR-RNAa: targeted activation of translation using dCas13 fusions to translation initiation factors

Tools for synthetically controlling gene expression are a cornerstone of genetic engineering. CRISPRi and CRISPRa technologies have been applied extensively for programmable modulation of gene transcription, but there are few such tools for targeted modulation of protein translation rates. Here, we...

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Detalles Bibliográficos
Autores principales: Otoupal, Peter B, Cress, Brady F, Doudna, Jennifer A, Schoeniger, Joseph S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410913/
https://www.ncbi.nlm.nih.gov/pubmed/35950485
http://dx.doi.org/10.1093/nar/gkac680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410913/
https://www.ncbi.nlm.nih.gov/pubmed/35950485
http://dx.doi.org/10.1093/nar/gkac680

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