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CRISPR-RNAa: targeted activation of translation using dCas13 fusions to translation initiation factors
Tools for synthetically controlling gene expression are a cornerstone of genetic engineering. CRISPRi and CRISPRa technologies have been applied extensively for programmable modulation of gene transcription, but there are few such tools for targeted modulation of protein translation rates. Here, we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410913/ https://www.ncbi.nlm.nih.gov/pubmed/35950485 http://dx.doi.org/10.1093/nar/gkac680 |