Precise tuning of bacterial translation initiation by non-equilibrium 5′-UTR unfolding observed in single mRNAs

Noncoding, structured 5′-untranslated regions (5′-UTRs) of bacterial messenger RNAs (mRNAs) can control translation efficiency by forming structures that either recruit or repel the ribosome. Here we exploit a 5′-UTR embedded preQ(1)-sensing, pseudoknotted translational riboswitch to probe how bindi...

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Detalles Bibliográficos
Autores principales: Ray, Sujay, Dandpat, Shiba S, Chatterjee, Surajit, Walter, Nils G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410914/
https://www.ncbi.nlm.nih.gov/pubmed/35892287
http://dx.doi.org/10.1093/nar/gkac635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410914/
https://www.ncbi.nlm.nih.gov/pubmed/35892287
http://dx.doi.org/10.1093/nar/gkac635

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