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Inference of cell state transitions and cell fate plasticity from single-cell with MARGARET

Despite recent advances in inferring cellular dynamics using single-cell RNA-seq data, existing trajectory inference (TI) methods face difficulty in accurately reconstructing the cell-state manifold and cell-fate plasticity for complex topologies. Here, we present MARGARET (https://github.com/Zafar-...

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Detalles Bibliográficos
Autores principales: Pandey, Kushagra, Zafar, Hamim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410915/
https://www.ncbi.nlm.nih.gov/pubmed/35639499
http://dx.doi.org/10.1093/nar/gkac412