Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF-κB Pathway Inhibition in Mice

BACKGROUND: Recent genetic studies indicated that variants of autophagy genes were associated with the predisposition of Crohn's disease (CD). The autophagy deficiency may affect the innate and adaptive immunity, which is related to persistent and excessive inflammation of the bowel. However, i...

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Detalles Bibliográficos
Autores principales: Ni, Zhen, Li, Hao, Mu, Dong, Hou, Juanni, Liu, Xiaoyan, Tang, Shanhong, Zheng, Shumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410967/
https://www.ncbi.nlm.nih.gov/pubmed/36032781
http://dx.doi.org/10.1155/2022/2923216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410967/
https://www.ncbi.nlm.nih.gov/pubmed/36032781
http://dx.doi.org/10.1155/2022/2923216

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