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Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA

ADP-ribosylation is an ancient, highly conserved, and reversible covalent modification critical for a variety of endogenous processes in both prokaryotes and eukaryotes. ADP-ribosylation targets proteins, nucleic acids, and small molecules (including antibiotics). ADP-ribosylation signalling involve...

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Detalles Bibliográficos
Autores principales: Hloušek-Kasun, Andrea, Mikolčević, Petra, Rack, Johannes Gregor Matthias, Tromans-Coia, Callum, Schuller, Marion, Jankevicius, Gytis, Matković, Marija, Bertoša, Branimir, Ahel, Ivan, Mikoč, Andreja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411070/
https://www.ncbi.nlm.nih.gov/pubmed/36051881
http://dx.doi.org/10.1016/j.csbj.2022.08.002