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Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway

The overexpression of Epidermal Growth Factor Receptor (EGFR) and dysregulation of its downstream effector pathways are important molecular hallmarks of oral cancers. Present study investigates the chemopreventive potential of polymeric black tea polyphenols (PBPs)/thearubigins (TRs) in the hamster...

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Detalles Bibliográficos
Autores principales: Nimbalkar, Vaishnavi K., Gangar, Jeet, Shai, Saptarsi, Rane, Pallavi, Mohanta, Subham Kumar, Kannan, Sadhana, Ingle, Arvind, Mittal, Neha, Rane, Swapnil, Mahimkar, Manoj B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411124/
https://www.ncbi.nlm.nih.gov/pubmed/36008552
http://dx.doi.org/10.1038/s41598-022-18680-0