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Nanoscale segregation of channel and barrier claudins enables paracellular ion flux

The paracellular passage of ions and small molecules across epithelia is controlled by tight junctions, complex meshworks of claudin polymers that form tight seals between neighboring cells. How the nanoscale architecture of tight junction meshworks enables paracellular passage of specific ions or s...

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Detalles Bibliográficos
Autores principales: Gonschior, Hannes, Schmied, Christopher, Van der Veen, Rozemarijn Eva, Eichhorst, Jenny, Himmerkus, Nina, Piontek, Jörg, Günzel, Dorothee, Bleich, Markus, Furuse, Mikio, Haucke, Volker, Lehmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411157/
https://www.ncbi.nlm.nih.gov/pubmed/36008380
http://dx.doi.org/10.1038/s41467-022-32533-4