CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis

Dysregulation of Hippo pathway leads to hyperactivation of YAP-TEAD transcriptional complex in various cancers, including colorectal cancer (CRC). In this study, we observed that HHEX (Hematopoietically expressed homeobox) may enhance transcription activity of the YAP-TEAD complex. HHEX associates w...

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Detalles Bibliográficos
Autores principales: Guo, Yuegui, Zhu, Zhehui, Huang, Zhenyu, Cui, Long, Yu, Wei, Hong, Wanjin, Zhou, Zhaocai, Du, Peng, Liu, Chen-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411202/
https://www.ncbi.nlm.nih.gov/pubmed/36008411
http://dx.doi.org/10.1038/s41467-022-32674-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411202/
https://www.ncbi.nlm.nih.gov/pubmed/36008411
http://dx.doi.org/10.1038/s41467-022-32674-6

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