Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes

Type 2 diabetes is an independent risk factor for non-alcoholic steatohepatitis (NASH) progression and its mediators have not been resolved. In this study, a pathogenic role of cellular communication network factor 2 (CCN2) protein in NASH pathology, was investigated in an established preclinical NA...

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Detalles Bibliográficos
Autores principales: Ren, Jing, Wang, Xiaoyu, Parry, Sarah N., Yee, Christine, Gorrell, Mark D., McLennan, Susan V., Twigg, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411483/
https://www.ncbi.nlm.nih.gov/pubmed/35038159
http://dx.doi.org/10.1007/s12079-022-00667-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411483/
https://www.ncbi.nlm.nih.gov/pubmed/35038159
http://dx.doi.org/10.1007/s12079-022-00667-1

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