Ginsenoside Rg5 allosterically interacts with P2RY(12) and ameliorates deep venous thrombosis by counteracting neutrophil NETosis and inflammatory response

BACKGROUND: Deep venous thrombosis (DVT) highly occurs in patients with severe COVID-19 and probably accounted for their high mortality. DVT formation is a time-dependent inflammatory process in which NETosis plays an important role. However, whether ginsenoside Rg5 from species of Panax genus could...

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Detalles Bibliográficos
Autores principales: Chen, Ziyu, Wang, Gaorui, Xie, Xueqing, Liu, Heng, Liao, Jun, Shi, Hailian, Chen, Min, Lai, Shusheng, Wang, Zhengtao, Wu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411522/
https://www.ncbi.nlm.nih.gov/pubmed/36032109
http://dx.doi.org/10.3389/fimmu.2022.918476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411522/
https://www.ncbi.nlm.nih.gov/pubmed/36032109
http://dx.doi.org/10.3389/fimmu.2022.918476

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