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Immunogenicity and toxicity of AAV gene therapy
Gene transfer using adeno-associated viral (AAV) vectors has made tremendous progress in the last decade and has achieved cures of debilitating diseases such as hemophilia A and B. Nevertheless, progress is still being hampered by immune responses against the AAV capsid antigens or the transgene pro...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411526/ https://www.ncbi.nlm.nih.gov/pubmed/36032092 http://dx.doi.org/10.3389/fimmu.2022.975803 |