Exogenous Urokinase Inhibits Proteasomal Degradation of Its Cognate Urokinase Plasminogen Activator Receptor

Acute pulmonary embolism (APE) is a debilitating condition with high incidence and mortality rates. APE is widely treated with the serine protease urokinase or urokinase-type plasminogen activator (uPA) that functions by resolving blood clots via catalyzing the conversion of plasminogen to plasmin....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Ran, Liu, Ting-Wei, Liu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411529/
https://www.ncbi.nlm.nih.gov/pubmed/36034808
http://dx.doi.org/10.3389/fphar.2022.754271