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Exogenous Urokinase Inhibits Proteasomal Degradation of Its Cognate Urokinase Plasminogen Activator Receptor

Acute pulmonary embolism (APE) is a debilitating condition with high incidence and mortality rates. APE is widely treated with the serine protease urokinase or urokinase-type plasminogen activator (uPA) that functions by resolving blood clots via catalyzing the conversion of plasminogen to plasmin....

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Detalles Bibliográficos
Autores principales:	Zhu, Ran, Liu, Ting-Wei, Liu, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411529/ https://www.ncbi.nlm.nih.gov/pubmed/36034808 http://dx.doi.org/10.3389/fphar.2022.754271

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