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Regulation of MMP9 transcription by ETS1 in immortalized salivary gland epithelial cells of patients with salivary hypofunction and primary Sjögren’s syndrome
Primary Sjögren’s syndrome (pSS) patients exhibit enhanced degradation of the salivary epithelium initially through MMP9 overexpression. We assessed the expression of MMP9 and an associated transcription factor, ETS1, in primary salivary gland epithelial cells (SGECs) and investigated potential regu...
Autores principales: | Noll, Braxton, Mougeot, Farah Bahrani, Brennan, Michael T., Mougeot, Jean-Luc C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411565/ https://www.ncbi.nlm.nih.gov/pubmed/36008454 http://dx.doi.org/10.1038/s41598-022-18576-z |
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