Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids

Pediatric hepatoblastoma is the most common primary liver cancer in infants and children. Studies of hepatoblastoma that focus exclusively on tumor cells demonstrate sparse somatic mutations and a common cell of origin, the hepatoblast, across patients. In contrast to the homogeneity these studies w...

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Detalles Bibliográficos
Autores principales: Song, Hanbing, Bucher, Simon, Rosenberg, Katherine, Tsui, Margaret, Burhan, Deviana, Hoffman, Daniel, Cho, Soo-Jin, Rangaswami, Arun, Breese, Marcus, Leung, Stanley, Ventura, María V. Pons, Sweet-Cordero, E. Alejandro, Huang, Franklin W., Nijagal, Amar, Wang, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411569/
https://www.ncbi.nlm.nih.gov/pubmed/36008377
http://dx.doi.org/10.1038/s41467-022-32473-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411569/
https://www.ncbi.nlm.nih.gov/pubmed/36008377
http://dx.doi.org/10.1038/s41467-022-32473-z

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