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Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety

Tocopheryl succinate (Tsuc) is a succinic acid ester of the well-known antioxidant α-tocopherol (T). Tsuc exhibits various biological activities, including tumor growth suppression via activation of cell signaling and prevention of lipid accumulation in mouse adipocyte 3T3-L1 cells. The latter findi...

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Detalles Bibliográficos
Autores principales: Yamasaki, Misaki, Seto, Yuika, Ozono, Mizune, Nakao, Michiyasu, Shigenaga, Akira, Otaka, Akira, Sano, Shigeki, Kogure, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411580/
https://www.ncbi.nlm.nih.gov/pubmed/36032400
http://dx.doi.org/10.1016/j.bbrep.2022.101329