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Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety
Tocopheryl succinate (Tsuc) is a succinic acid ester of the well-known antioxidant α-tocopherol (T). Tsuc exhibits various biological activities, including tumor growth suppression via activation of cell signaling and prevention of lipid accumulation in mouse adipocyte 3T3-L1 cells. The latter findi...
Autores principales: | Yamasaki, Misaki, Seto, Yuika, Ozono, Mizune, Nakao, Michiyasu, Shigenaga, Akira, Otaka, Akira, Sano, Shigeki, Kogure, Kentaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411580/ https://www.ncbi.nlm.nih.gov/pubmed/36032400 http://dx.doi.org/10.1016/j.bbrep.2022.101329 |
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