Specificity of TGF-β1 signal designated by LRRC33 and integrin α(V)β(8)

Myeloid lineage cells present the latent form of transforming growth factor-β1 (L-TGF-β1) to the membrane using an anchor protein LRRC33. Integrin α(V)β(8) activates extracellular L-TGF-β1 to trigger the downstream signaling functions. However, the mechanism designating the specificity of TGF-β1 pre...

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Detalles Bibliográficos
Autores principales: Duan, Zelin, Lin, Xuezhen, Wang, Lixia, Zhen, Qiuxin, Jiang, Yuefeng, Chen, Chuxin, Yang, Jing, Lee, Chia-Hsueh, Qin, Yan, Li, Ying, Zhao, Bo, Wang, Jianchuan, Zhang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411592/
https://www.ncbi.nlm.nih.gov/pubmed/36008481
http://dx.doi.org/10.1038/s41467-022-32655-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411592/
https://www.ncbi.nlm.nih.gov/pubmed/36008481
http://dx.doi.org/10.1038/s41467-022-32655-9

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