Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

More than 70% of human breast cancers (BCs) are estrogen receptor α-positive (ER(+)). A clinical challenge of ER(+) BC is that they can recur decades after initial treatments. Mechanisms governing latent disease remain elusive due to lack of adequate in vivo models. We compare intraductal xenografts...

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Detalles Bibliográficos
Autores principales: Aouad, Patrick, Zhang, Yueyun, De Martino, Fabio, Stibolt, Céline, Ali, Simak, Ambrosini, Giovanna, Mani, Sendurai A., Maggs, Kelly, Quinn, Hazel M., Sflomos, George, Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411634/
https://www.ncbi.nlm.nih.gov/pubmed/36008376
http://dx.doi.org/10.1038/s41467-022-32523-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411634/
https://www.ncbi.nlm.nih.gov/pubmed/36008376
http://dx.doi.org/10.1038/s41467-022-32523-6

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