Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

More than 70% of human breast cancers (BCs) are estrogen receptor α-positive (ER(+)). A clinical challenge of ER(+) BC is that they can recur decades after initial treatments. Mechanisms governing latent disease remain elusive due to lack of adequate in vivo models. We compare intraductal xenografts...

Descripción completa

Detalles Bibliográficos
Autores principales: Aouad, Patrick, Zhang, Yueyun, De Martino, Fabio, Stibolt, Céline, Ali, Simak, Ambrosini, Giovanna, Mani, Sendurai A., Maggs, Kelly, Quinn, Hazel M., Sflomos, George, Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411634/
https://www.ncbi.nlm.nih.gov/pubmed/36008376
http://dx.doi.org/10.1038/s41467-022-32523-6

Ejemplares similares

Ejemplares similares