KMT5B is required for early motor development

Disruptive variants in lysine methyl transferase 5B (KMT5B/SUV4-20H1) have been identified as likely-pathogenic among humans with neurodevelopmental phenotypes including motor deficits (i.e., hypotonia and motor delay). However, the role that this enzyme plays in early motor development is largely u...

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Detalles Bibliográficos
Autores principales: Hulen, Jason, Kenny, Dorothy, Black, Rebecca, Hallgren, Jodi, Hammond, Kelley G., Bredahl, Eric C., Wickramasekara, Rochelle N., Abel, Peter W., Stessman, Holly A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411648/
https://www.ncbi.nlm.nih.gov/pubmed/36035149
http://dx.doi.org/10.3389/fgene.2022.901228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411648/
https://www.ncbi.nlm.nih.gov/pubmed/36035149
http://dx.doi.org/10.3389/fgene.2022.901228

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