Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner

The newly emerged severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) can result in dysregulated interferon (IFN) responses that contribute to disease severity. The papain-like protease of SARS-CoV-2 (SCoV2-PLpro) has been previously reported to attenuate IFN responses, but the under...

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Detalles Bibliográficos
Autores principales: Ran, Xiang-Hong, Zhu, Jia-Wu, Chen, Ya-Yun, Ni, Run-Ze, Mu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411789/
https://www.ncbi.nlm.nih.gov/pubmed/36032116
http://dx.doi.org/10.3389/fimmu.2022.947272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411789/
https://www.ncbi.nlm.nih.gov/pubmed/36032116
http://dx.doi.org/10.3389/fimmu.2022.947272

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