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Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner
The newly emerged severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) can result in dysregulated interferon (IFN) responses that contribute to disease severity. The papain-like protease of SARS-CoV-2 (SCoV2-PLpro) has been previously reported to attenuate IFN responses, but the under...
Autores principales: | Ran, Xiang-Hong, Zhu, Jia-Wu, Chen, Ya-Yun, Ni, Run-Ze, Mu, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411789/ https://www.ncbi.nlm.nih.gov/pubmed/36032116 http://dx.doi.org/10.3389/fimmu.2022.947272 |
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