A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish

An integrated evaluation of the tissue distribution and pharmacodynamic properties of a therapeutic is essential for successful translation to the clinic. To date, however, cost-effective methods to measure these parameters at the systems level in model organisms are lacking. Here, we introduce a mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Jackstadt, Madelyn M., Chamberlain, Casey A., Doonan, Steven R., Shriver, Leah P., Patti, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411795/
https://www.ncbi.nlm.nih.gov/pubmed/35972155
http://dx.doi.org/10.1242/dmm.049550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411795/
https://www.ncbi.nlm.nih.gov/pubmed/35972155
http://dx.doi.org/10.1242/dmm.049550

Ejemplares similares