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A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish
An integrated evaluation of the tissue distribution and pharmacodynamic properties of a therapeutic is essential for successful translation to the clinic. To date, however, cost-effective methods to measure these parameters at the systems level in model organisms are lacking. Here, we introduce a mu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411795/ https://www.ncbi.nlm.nih.gov/pubmed/35972155 http://dx.doi.org/10.1242/dmm.049550 |