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Inhibitory effect of (pro)renin receptor decoy inhibitor PRO20 on endoplasmic reticulum stress during cardiac remodeling

Background: Ectopic activation of renin-angiotensin-system contributes to cardiovascular and renal diseases. (Pro)renin receptor (PRR) binds to renin and prorenin, participating in the progression of nephrology. However, whether PRR could be considered as a therapeutic target for cardiac remodeling...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Cheng, Yun-Jiu, Luo, Chang-Jun, Yu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411812/
https://www.ncbi.nlm.nih.gov/pubmed/36034809
http://dx.doi.org/10.3389/fphar.2022.940365