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Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome

Women are disproportionately affected by Alzheimer's disease (AD), yet little is known about sex-specific effects on the development of AD in the Down syndrome (DS) population. DS is caused by a full or partial triplication of chromosome 21, which harbors the amyloid precursor protein (APP) gen...

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Detalles Bibliográficos
Autores principales: Andrews, Elizabeth J., Martini, Alessandra C., Head, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411995/
https://www.ncbi.nlm.nih.gov/pubmed/36033603
http://dx.doi.org/10.3389/fnins.2022.954999