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Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome
Women are disproportionately affected by Alzheimer's disease (AD), yet little is known about sex-specific effects on the development of AD in the Down syndrome (DS) population. DS is caused by a full or partial triplication of chromosome 21, which harbors the amyloid precursor protein (APP) gen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411995/ https://www.ncbi.nlm.nih.gov/pubmed/36033603 http://dx.doi.org/10.3389/fnins.2022.954999 |