Cargando…

Polymorphism in alpha-synuclein oligomers and its implications in toxicity under disease conditions

The major hallmark of Parkinson’s disease (PD) is represented by the formation of pathological protein plaques largely consisting of α-synuclein (αSN) amyloid fibrils. Nevertheless, the implications of αSN oligomers in neuronal impairments and disease progression are more importantly highlighted tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoo, Je Min, Lin, Yuxi, Heo, Yunseok, Lee, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412080/
https://www.ncbi.nlm.nih.gov/pubmed/36032665
http://dx.doi.org/10.3389/fmolb.2022.959425