Properties of Adenovirus Vectors with Increased Affinity to DSG2 and the Potential Benefits of Oncolytic Approaches and Gene Therapy

Carcinomas are characterized by a widespread upregulation of intercellular junctions that create a barrier to immune response and drug therapy. Desmoglein 2 (DSG2) represents such a junction protein and serves as one adenovirus receptor. Importantly, the interaction between human adenovirus type 3 (...

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Detalles Bibliográficos
Autores principales: Bahlmann, Nora A., Tsoukas, Raphael L., Erkens, Sebastian, Wang, Hongjie, Jönsson, Franziska, Aydin, Malik, Naumova, Ella A., Lieber, André, Ehrhardt, Anja, Zhang, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412290/
https://www.ncbi.nlm.nih.gov/pubmed/36016457
http://dx.doi.org/10.3390/v14081835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412290/
https://www.ncbi.nlm.nih.gov/pubmed/36016457
http://dx.doi.org/10.3390/v14081835

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