Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against Mycobacterium tuberculosis

The development of novel pharmaceutical tools to efficiently tackle tuberculosis is the order of the day due to the rapid development of resistant strains of Mycobacterium tuberculosis. Herein, we report novel potential formulations of a repurposed drug, the antimalarial mefloquine (MFL), which was...

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Detalles Bibliográficos
Autores principales: Silva, Dário, Lopes, Márcio V. C., Petrovski, Željko, Santos, Miguel M., Santos, Jussevania P., Yamada-Ogatta, Sueli F., Bispo, Marcelle L. F., de Souza, Marcus V. N., Duarte, Ana Rita C., Lourenço, Maria C. S., Gonçalves, Raoni Schroeder B., Branco, Luis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412322/
https://www.ncbi.nlm.nih.gov/pubmed/36014405
http://dx.doi.org/10.3390/molecules27165167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412322/
https://www.ncbi.nlm.nih.gov/pubmed/36014405
http://dx.doi.org/10.3390/molecules27165167

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