Pharmacophore-Model-Based Drug Repurposing for the Identification of the Potential Inhibitors Targeting the Allosteric Site in Dengue Virus NS5 RNA-Dependent RNA Polymerase

Dengue virus (DENV) is the causative agent of DENV infection. To tackle DENV infection, the development of therapeutic molecules as direct-acting antivirals (DAAs) has been demonstrated as a truly effective approach. Among various DENV drug targets, non-structural protein 5 (NS5)—a highly conserved...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjay, Bajrai, Leena H., Faizo, Arwa A., Khateb, Aiah M., Alkhaldy, Areej A., Rana, Rashmi, Azhar, Esam I., Dwivedi, Vivek Dhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412353/
https://www.ncbi.nlm.nih.gov/pubmed/36016449
http://dx.doi.org/10.3390/v14081827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412353/
https://www.ncbi.nlm.nih.gov/pubmed/36016449
http://dx.doi.org/10.3390/v14081827

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