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Pharmacophore-Model-Based Drug Repurposing for the Identification of the Potential Inhibitors Targeting the Allosteric Site in Dengue Virus NS5 RNA-Dependent RNA Polymerase

Dengue virus (DENV) is the causative agent of DENV infection. To tackle DENV infection, the development of therapeutic molecules as direct-acting antivirals (DAAs) has been demonstrated as a truly effective approach. Among various DENV drug targets, non-structural protein 5 (NS5)—a highly conserved...

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Detalles Bibliográficos
Autores principales:	Kumar, Sanjay, Bajrai, Leena H., Faizo, Arwa A., Khateb, Aiah M., Alkhaldy, Areej A., Rana, Rashmi, Azhar, Esam I., Dwivedi, Vivek Dhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412353/ https://www.ncbi.nlm.nih.gov/pubmed/36016449 http://dx.doi.org/10.3390/v14081827

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