Investigation of Molecular Weight, Polymer Concentration and Process Parameters Factors on the Sustained Release of the Anti-Multiple-Sclerosis Agent Teriflunomide from Poly(ε-caprolactone) Electrospun Nanofibrous Matrices

In the current work, a series of PCL polyesters with different molecular weights was synthesized and used for the fabrication of nanofibrous patches via electrospinning, as sustained release matrices for leflunomide’s active metabolite, teriflunomide (TFL). The electrospinning conditions for each sa...

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Detalles Bibliográficos
Autores principales: Bikiaris, Nikolaos D., Koumentakou, Ioanna, Michailidou, Georgia, Kostoglou, Margaritis, Vlachou, Marilena, Barmpalexis, Panagiotis, Karavas, Evangelos, Papageorgiou, George Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412398/
https://www.ncbi.nlm.nih.gov/pubmed/36015319
http://dx.doi.org/10.3390/pharmaceutics14081693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412398/
https://www.ncbi.nlm.nih.gov/pubmed/36015319
http://dx.doi.org/10.3390/pharmaceutics14081693

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