A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cytotoxicity and DNA/Protein Binding Studies

“Drug repositioning” is a modern strategy used to uncover new applications for out-of-date drugs. In this context, nalidixic acid, the first member of the quinolone class with limited use today, has been selected to obtain nine new metal complexes with lanthanide cations (La(3+), Sm(3+), Eu(3+), Gd(...

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Detalles Bibliográficos
Autores principales: Maciuca, Ana-Madalina, Munteanu, Alexandra-Cristina, Mihaila, Mirela, Badea, Mihaela, Olar, Rodica, Nitulescu, George Mihai, Munteanu, Cristian V. A., Uivarosi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412414/
https://www.ncbi.nlm.nih.gov/pubmed/36015158
http://dx.doi.org/10.3390/ph15081010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412414/
https://www.ncbi.nlm.nih.gov/pubmed/36015158
http://dx.doi.org/10.3390/ph15081010

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