Therapeutic Drug Monitoring of Ivacaftor, Lumacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis: Where Are We Now?

Drugs modulating the cystic fibrosis transmembrane conductance regulator (CFTR) protein, namely ivacaftor, lumacaftor, tezacaftor, and elexacaftor, are currently revolutionizing the management of patients with cystic fibrosis (CF), particularly those with at least one F508del variant (up to 85% of p...

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Detalles Bibliográficos
Autores principales: Choong, Eva, Sauty, Alain, Koutsokera, Angela, Blanchon, Sylvain, André, Pascal, Decosterd, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412421/
https://www.ncbi.nlm.nih.gov/pubmed/36015300
http://dx.doi.org/10.3390/pharmaceutics14081674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412421/
https://www.ncbi.nlm.nih.gov/pubmed/36015300
http://dx.doi.org/10.3390/pharmaceutics14081674

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