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Pharmacovigilance of Herb-Drug Interactions: A Pharmacokinetic Study on the Combined Administration of Tripterygium Glycosides Tablets and Leflunomide Tablets in Rats by LC-MS/MS

A popular and widely used combination therapy of leflunomide (LEF) and Tripterygium glycosides tablets (TGT(S)) has become a valuable clinical tool in China for the treatment of rheumatoid arthritis. This regimen has not been evaluated either in terms of interaction or toxicity, even given the risin...

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Detalles Bibliográficos
Autores principales: Boucetta, Hamza, Wu, Wei, Hong, Tao, Cheng, Rui, Jiang, Jing, Liu, Chengxi, Song, Min, Hang, Taijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412457/
https://www.ncbi.nlm.nih.gov/pubmed/36015140
http://dx.doi.org/10.3390/ph15080991