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Diindolylmethane Derivatives: New Selective Blockers for T-Type Calcium Channels

The natural product indole-3-carbinol (I3C) and its major digestive product 3,3′-diindolylmethane (DIM) have shown clinical promise in multiple forms of cancer including breast cancer. In this study, we explored the calcium channel activity of DIM, its synthetic derivative 3,3′-Diindolylmethanone (D...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Neupane, Pratik, Ragnarsson, Lotten, Capon, Robert J., Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412534/
https://www.ncbi.nlm.nih.gov/pubmed/36005664
http://dx.doi.org/10.3390/membranes12080749