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Cytotoxicity and Apoptotic Mechanism of 2-Hydroxyethyl Methacrylate via Genotoxicity and the Mitochondrial-Dependent Intrinsic Caspase Pathway and Intracellular Reactive Oxygen Species Accumulation in Macrophages

Macrophages are mainly active cells of the immune system and play a role in the defense of pathogens. However, the overactivation of macrophages by fatal pathogens can result in toxic responses. 2-hydroxyethyl methacrylate (HEMA), which is a hydrophilic monomer, is used in dental adhesive reagents a...

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Detalles Bibliográficos
Autores principales: Lee, Chien-Ying, Ho, Yung-Chuan, Lee, Shiuan-Shinn, Li, Yi-Ching, Lai, Mei-Yu, Kuan, Yu-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412604/
https://www.ncbi.nlm.nih.gov/pubmed/36015636
http://dx.doi.org/10.3390/polym14163378