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Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

BACKGROUND: Complement lectin pathway components, in particular mannan-binding lectin (MBL) and MBL-associated serine proteases (MASPs) have been shown to interact with coagulation factors and contribute to clot formation. Here we investigated the role of MBL and MASP-1 in the haemostatic response f...

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Detalles Bibliográficos
Autores principales: Golomingi, Murielle, Kohler, Jessie, Jenny, Lorenz, Hardy, Elaissa T., Dobó, József, Gál, Péter, Pál, Gábor, Kiss, Bence, Lam, Wilbur A., Schroeder, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412763/
https://www.ncbi.nlm.nih.gov/pubmed/36032172
http://dx.doi.org/10.3389/fimmu.2022.948190