mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses

Translocated lipopolysaccharide (LPS) activates monocytes via TLR4 and is hypothesized to increase cardiovascular disease risk in persons living with HIV. We tested whether mTOR activity supports LPS-stimulated monocyte production of pro-inflammatory cytokines and tissue factor (TF), as it propels t...

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Detalles Bibliográficos
Autores principales: Lund, Nina C., Kayode, Yetunde, McReynolds, Melanie R., Clemmer, Deanna C., Hudson, Hannah, Clerc, Isabelle, Hong, Hee-Kyung, Brenchley, Jason M., Bass, Joseph, D’Aquila, Richard T., Taylor, Harry E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412771/
https://www.ncbi.nlm.nih.gov/pubmed/36028574
http://dx.doi.org/10.1038/s42003-022-03804-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412771/
https://www.ncbi.nlm.nih.gov/pubmed/36028574
http://dx.doi.org/10.1038/s42003-022-03804-z

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