Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer

Gastric cancer is a common malignant tumor that threatens human health, and its occurrence and development mechanism is a complex process involving multiple genes and multiple signals. Signal transducer and activator of transcription 3 (STAT3) has been elucidated as a promising target for developing...

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Detalles Bibliográficos
Autores principales: Li, Haobin, Wang, Lingling, Cao, Fei, Yu, Dehua, Yang, Jing, Yu, Xuefei, Dong, Jinyun, Qin, Jiang-Jiang, Guan, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412775/
https://www.ncbi.nlm.nih.gov/pubmed/36034876
http://dx.doi.org/10.3389/fphar.2022.944455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412775/
https://www.ncbi.nlm.nih.gov/pubmed/36034876
http://dx.doi.org/10.3389/fphar.2022.944455

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