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Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer
Gastric cancer is a common malignant tumor that threatens human health, and its occurrence and development mechanism is a complex process involving multiple genes and multiple signals. Signal transducer and activator of transcription 3 (STAT3) has been elucidated as a promising target for developing...
Autores principales: | Li, Haobin, Wang, Lingling, Cao, Fei, Yu, Dehua, Yang, Jing, Yu, Xuefei, Dong, Jinyun, Qin, Jiang-Jiang, Guan, Xiaoqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412775/ https://www.ncbi.nlm.nih.gov/pubmed/36034876 http://dx.doi.org/10.3389/fphar.2022.944455 |
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