Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics

Cellular glutamine synthesis is thought to be an important resistance factor in protecting cells from nutrient deprivation and may also contribute to drug resistance. The application of ‟targeted stable isotope resolved metabolomics” allowed to directly measure the activity of glutamine synthetase i...

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Detalles Bibliográficos
Autores principales: Bayram, Șafak, Razzaque, Yasmin Sophiya, Geisberger, Sabrina, Pietzke, Matthias, Fürst, Susanne, Vechiatto, Carolina, Forbes, Martin, Mastrobuoni, Guido, Kempa, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412915/
https://www.ncbi.nlm.nih.gov/pubmed/36032676
http://dx.doi.org/10.3389/fmolb.2022.859787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412915/
https://www.ncbi.nlm.nih.gov/pubmed/36032676
http://dx.doi.org/10.3389/fmolb.2022.859787

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